Ethylene oxide (EO) remains the sterilization method of choice for approximately 50% of all single-use medical devices worldwide, thanks to its excellent material compatibility and scalability. As the industry advances toward more sustainable practices, innovative optimization strategies are helping reduce EO use while maintaining required sterility assurance levels (SAL) to help ensure patient safety.
In this technical webinar, experts from Gerresheimer and Sterigenics share a real‑world case study demonstrating how EO sterilization cycles for pre‑fillable glass syringes can be optimized to significantly reduce EO usage while maintaining a sterility assurance level (SAL) of 10⁻⁶.
Attendees will learn how a systematic re‑evaluation of cycle design, load configuration, and validation strategy enabled meaningful reductions in EO concentration and total gas usage, including shortened cycle times, and improved operational efficiency—without compromising product safety or regulatory compliance.
Key Learning Objectives
- How key EO cycle parameters—including temperature, vacuum depth, gas injection strategy, and dwell time—directly impact sterilization efficiency and sustainability.
- Why process challenge device (PCD) selection and modern validation approaches can prevent over‑challenging cycles and unlock significant time and gas reductions.
- How EO optimization supports environmental goals by lowering EO consumption, reducing fugitive emissions, and improving overall safety and throughput.